Dispensaries may sell a variety of “CBD-rich” products that are high in CBD and relatively low in THC, including oils, tinctures, topicals, and vaping liquids. They may even sell buds or flower from marijuana strains that have been bred to have very low levels of THC, says Michael Backes, author of "Cannabis Pharmacy: The Practical Guide to Medical Marijuana" (Black Dog & Leventhal, 2014). For example, the strain “AC/DC” can be just 0.5 percent THC, barely above the cutoff allowed for CBD from hemp and much lower than the 20 percent or higher THC concentration typical of most marijuana strains, Backes says.
Cannabidiol and cannabidiolic acid work by binding to various receptor targets throughout the central nervous system and the rest of the body. Acting at these receptor sites, it exerts influence on the metabolism of various neurotransmitter systems. It seems like ‘snake oil’ that one compound can have all the beneficial effects listed above; however, cannabinoid receptors exist throughout the nervous system and it is known that such a ubiquitous receptor must be involved in nearly everything the nervous system does, just like serotonin and dopamine receptors. Dopamine affects pleasure, but also pain. Anxiety and also relaxation. Heart contraction and blood pressure. All of these systems are integrated so cannabinoid receptors will indeed have effects on all of these systems and exogenous cannabinoids from plants can definitely have therapeutic effects which are extensive.
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