As the cannabis plant awaits a high-stakes review from international health authorities, the U.S. Food and Drug Administration is inviting the public to weigh in on whether cannabis, CBD and other cannabis extracts should declassified as a controlled substance. The UN’s World Health Organization made a preliminary announcement in December that CBD has a low […]
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In addition to THC, Meyer and consumers also need to worry about whether CBD products have contaminants. That’s because cannabis plants readily absorb heavy metals, pesticides, and other potentially harmful chemicals that may be in the soil or water, says Kyle Boyar, a cannabis scientist at Medicinal Genomics, a company that develops tests that help labs comply with state rules. To protect against that risk, cannabis plants should be tested frequently while they are growing, and finished products should be tested, using validated methods, too, Boyar says.

The Hemp Industries Association (HIA) reported total U.S. retail sales of hemp products of nearly $700 million in 2016. HIA claims that U.S. hemp retail sales have grown by about 10% to more than 20% annually since 2011. Mostly, this growth is attributable to sales of hemp-based care products, supplements, and foods. Together, these categories accounted for more than two-thirds of the value of U.S. retail sales in 2016.

Research is beginning to show that CBD is different than other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. (2)
Cannabidiol and cannabidiolic acid work by binding to various receptor targets throughout the central nervous system and the rest of the body.  Acting at these receptor sites, it exerts influence on the metabolism of various neurotransmitter systems.  It seems like ‘snake oil’ that one compound can have all the beneficial effects listed above; however, cannabinoid receptors exist throughout the nervous system and it is known that such a ubiquitous receptor must be involved in nearly everything the nervous system does, just like serotonin and dopamine receptors.  Dopamine affects pleasure, but also pain.  Anxiety and also relaxation.  Heart contraction and blood pressure.  All of these systems are integrated so cannabinoid receptors will indeed have effects on all of these systems and exogenous cannabinoids from plants can definitely have therapeutic effects which are extensive.
HempWorx CBD is an interesting brand that has no issue with transparency in terms of how they operate as a business, and where they source their raw hemp plant material from. Also, one of the main things that stands out to me as that they’re one of the only companies I know of that offers specific dosing guidelines for a range of serious medical conditions. This is a bit odd, however, as they also make it clear that CBD is not approved by the FDA as a medicine, and thus none of their products are designed to “treat, cure, or prevent” any disease.
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